Osteo-articular biomechanics (biomechanics, bone, mechanobiology)

[Thibault.Lemaire]

The Biomechanics group of the Multiscale Modelling and Simulation CNRS Laboratory in the University Paris Est is interrested in describing bone tissue biomechanical behaviour. In particular, they develop: i/ multiscale in silico studies devoted to mimic bone remodelling process by quantifying multiphysical phenomena (poroelasticity, interstitial fluid flow, electro-chemistry, chemical transport...); ii/ multiscale and ultrasonic characterization of bone tissue; iii/ tissue engineering protocols using different drinving forces (hydraulic effect, electro-osmosis, chemo attraction...).

Every collaboration is welcome.

Contact: thibault.lemaire [at] univ-paris-est.fr





Selected papers:

Lemaire T., Naili S., Rémond A. Study of the influence of fibrous pericellular matrix in the cortical interstitial fluid movement with hydroelectrochemical effects. Journal of Biomechanical Engineering (ASME), 130, 1-11, 2008.

Rémond A., Naili S., Lemaire T. Interstitial fluid flow in the osteon with spatial gradients of mechanical properties: a finite element study. Biomechanics and Modeling in Mechanobiology, 7, 487-495, 2008.

Haïat G., Padilla F., Svrcekova M., Chevalier Y., Pahr D., Laugier P. and Zysset P., “Relationship between ultrasonic parameters and apparent bone elastic modulus bone: a numerical approach”, J. Biomech. 42(13) (2009) pp 2033-2039

Sansalone V., Lemaire T., Naïli S., Variational homogenization for modelling fibrillar structures in bone. Mechanics Research Communications, 36(2), 265-273, 2009.

Haïat G., Naili S., Grimal Q., Talmant M., Desceliers C., Soize C., “
Influence of a gradient of material properties on ultrasonic wave propagation in cortical bone:
application to axial transmission”, J Acoust Soc Am. 125(6) (2009) pp 4043-4052

Sansalone V., Naili S., Bousson V., Bergot C., Peyrin F., Zarka J., Laredo J.D., Haïat G., Determination of the heterogeneous anisotropic elastic properties of human femoral bone: From nanoscopic to organ scale. Journal of Biomechanics, 43(10), 1857-1863, 2010.

Nguyen V.-H., Naili S., Sansalone V., Simulation of ultrasonic wave propagation in anisotropic cancellous bone immersed in fluid. Wave Motion, 47(2), 117-129, 2010.

Oddou C., Lemaire T., Pierre J., David B. Hydrodynamics in Porous Media with Applications to Tissue Engineering. in “Porous Media :Applications in Biological Systems and Biotechnology”, 75-119, CRC Press, New-York (2010).