View Full Version : CV stefy (peptide, protein, membrane interaction)

Oct 4, 10, 07:41
Project coordinator: Dr. Stefania Galdiero, Asst Professor of General and Inorganic Chemistry

Protein Science Cover, 13, (2004); Guest Editor of a special volume of Protein & Peptide Letters on “Membrane Fusion Developments” 2009; European Patent N°:SCB 1911 EUR 2008 "Synthetic analogs of human beta-defensin having antimicrobial, antiviral andche motactic activity"; Provisional Patent Application N°61/285,619 2009 "Method for delivery of molecules into intracellular targets".

Recent Pubblications
1. S. Galdiero, M. Vitiello, M. D’Isanto, A. Falanga, M. Cantisani, H. Browne, C. Pedone, and M. Galdiero “The Identification and Characterisation of Fusogenic Domains in Herpesvirus Glycoprotein B Molecules”. ChemBioChem, 9 :758-67, (2008).
2. M. Vitello*, S. Galdiero*§, M. D’Isanto, M. D’Amico, C. Di Filippo, M. Cantisani, M. Galdiero, C. Pedone “Pathophysiological changes of gram-negative bacterial infection can be reproduced by a synthetic peptide mimicking loop L7 sequence of Haemophilus influenzae porin”. Microbes and Infections, 10, 657-663 (2008).
§Corresponding author
3. S. Galdiero, M. Vitiello, A. Falanga, M. D’Isanto, M. Cantisani, A. Kampanaraki, E. Benedetti, H. Browne, M. Galdiero “Peptides Containing Membrane-interacting Motifs Inhibit Herpes Simplex Virus type 1 Infectivity”. Peptides, 29, 1461-1471 (2008).
4. S. Galdiero, A. Falanga, M. Vitiello, L. Raiola, R. Fattorusso, H. Browne, C. Pedone, C.Isernia, M. Galdiero “Analysis of a Membrane Interacting Region af Herpes Simplex Virus Type1 Glycoprotein H” Journal Biological Chemistry, 283(44):29993-30009 (2008).
5. A. Falanga, M. Cantisani, C. Pedone, S. Galdiero “Membrane Fusion and Fission: enveloped viruses” Protein & Peptide Letters, 16 (7): 751-759 (2009).
6. S. Galdiero “Developments In Membrane Fusion” Editorial Protein & Peptide Letters, 16 (7): 711 (2009)
7. V. Severino, A. Chambery, M. Vitiello, M. Cantisani, S. Galdiero, M. Galdiero, L. Malorni, A. Di Maro, A. Parente “Proteomic analysis of human U937 cell line activation mediated by Haemophilus influenzae type b P2 porin and its surface-exposed loop 7”. Journal Proteome Research, 9(2):1050-1062 (2010).
8. S. Galdiero, Falanga A, Vitiello G, Vitiello M, Pedone C, D'Errico G, Galdiero M. "Role of membranotropic sequences from herpes simplex virus type I glycoproteins B and H in the fusion process.” Biochim Biophys Acta. 1798(3):579-591 (2010).
9. Vitiello M., Finamore E., Falanga A., Raieta K., Cantisani M., Pedone C., Galdiero M., Galdiero S. Viral Fusion Peptides Induce Several Signal Transduction Pathways Activation That Are Essential For Il-10 and -Interferon Production. Intervirology, 53(6):381-9 (2010).
10. O. Scudiero*, S. Galdiero*, M. Cantisani, R. Di Noto, M. Galdiero, M. D’Isanto, G. Naclerio, C. Pedone, G. Castaldo, F. Salvatore “Synthetic analogs of human beta-defensins display a more effective antimicrobial activity than wild-type peptides”. Antimicrobial Agents and Chemotherapy, 54(6):2312-22 (2010).
11. S. Galdiero, A. Falanga, M. Vitiello, L. Raiola, L. Russo, C. Pedone, C.Isernia, M. Galdiero “The presence of a single N-terminal histidine residue enhances the fusogenic properties of a Membranotropic peptide derived from herpes simplex virus type 1 glycoprotein H.” Journal Biological Chemistry, accetpted (2010).